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4-hydroxy Nebivolol hydrochloride

SKU: orb2283015

Description

4-Hydroxy Nebivolol is the primary active metabolite of the beta-blocker Nebivolol, formed via CYP2D6-mediated hydroxylation. This metabolite is a key tool for in vitro and in vivo pharmacological research, particularly in studies of cardiovascular drug metabolism, adrenergic receptor activity, and individual metabolic variability.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2717115-85-8
MW457.9
FormulaC22H25F2NO5?HCl
SMILESOC1C=2C(OC(C(CNCC(O)C3OC=4C(CC3)=CC(F)=CC4)O)C1)=CC=C(F)C2.Cl
TargetDrug Metabolite,Others,Adrenergic Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

4-hydroxy Nebivolol hydrochloride (orb2283015)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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