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4-Desmethyl-2-methyl celecoxib

SKU: orb3028585

Description

4-Desmethyl-2-methyl celecoxib (Compound 1g) is an orally active and selective cyclooxygenase-2 (COX-2) inhibitor, with an IC50 value of 0.069 μM. It possesses anti-inflammatory, analgesic, and antipyretic properties and can reduce prostaglandin synthesis. This compound is a promising candidate for research into inflammatory diseases and pain-related conditions, such as rheumatoid arthritis and osteoarthritis.

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Key Properties

CAS Number170569-99-0
MW381.372
FormulaC17H14F3N3O2S
SMILESO=S(=O)(N)C1=CC=C(C=C1)N2N=C(C=C2C=3C=CC=CC3C)C(F)(F)F
TargetCOX

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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4-Desmethyl-2-methyl celecoxib (orb3028585)

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