4-CPPC

• Catalog Number: orb1303690
• Category: Small Molecules
• Description: 4-CPPC
• CAS Number: 29553-70-6
• Purity: 98%
• MW: 287.22
• SMILES: OC(=O)C1=CC=CC(=C1)C1=CC(=NC=C1C(O)=O)C(O)=O
• Formula: C₁₄H₉NO₆
• Biological Activity: 4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.