4-CPPC

SKU: orb1303690

Description

4-CPPC is a selective small molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2) with an IC50 of 27 μM, showing over 16-fold selectivity versus MIF-1. It blocks MIF-2 binding to its receptor CD74 and inhibits downstream ERK1/2 phosphorylation in human fibroblasts, making it a useful tool for studying MIF-2-specific signaling pathways in immunological and inflammatory research.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 29553-70-6
• MW: 287.22
• Purity: 98.03% (May vary between batches)
• Formula: C₁₄H₉NO₆
• SMILES: OC(=O)C1=CC=CC(=C1)C1=CC(=NC=C1C(O)=O)C(O)=O
• Target: Others,CD74,MIF
• Solubility: DMSO:2.88 mg/mL (10.03 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

4CPPC, 4-CPPC, 4 CPPC

Compound Identifiers

PubChem CID

893698