4-amino-1,8-Naphthalimide

SKU: orb1306313

Description

4-Amino-1,8-naphthalimide (4-ANI) is a potent small molecule inhibitor of PARP, exhibiting an IC50 value of 180 nM. It is widely used in biochemical research to study DNA repair mechanisms and has been applied in both in vitro assays and in vivo models of cancer and oxidative stress.

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

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Key Properties

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CAS Number	1742-95-6
MW	212.2
Purity	95.51% (May vary between batches)
Formula	C₁₂H₈N₂O₂
SMILES	Nc1ccc2C(=O)NC(=O)c3cccc1c23
Target	PARP
Solubility	DMSO:3.6 mg/mL (16.97 mM)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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4 amino 1,8 Naphthalimide, 4-Aminonaphthalimide, 4amino1,8Naphthalimide, 4-amino-1,8-Naphthalimide, Inhibitor, inhibit, PARP, poly ADP ribose polymerase

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Compound Identifiers

PubChem CID

1720 ↗

Key Properties

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No computed properties available.

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