(3S,4R)-GNE-6893

SKU: orb2564406

Description

GNE-6893 is a potent and orally bioavailable small molecule inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1). It is used in cancer immunotherapy research to investigate HPK1's role as a negative regulator of T-cell function in both cellular assays and in vivo models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2415374-97-7
• MW: 453.47
• Formula: C₂₃H₂₄FN₅O₄
• SMILES: FC=1C(=CC2=C(C1N)C=NC(NC(O[C@H]3[C@H](C)COC3)=O)=C2)C=4C(C)=C5C(=NC4)OCCN5
• Target: MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146463535