3,5-Diiodothyropropionic acid

SKU: orb1308889

Description

3,5-Diiodothyropropionic acid is a synthetic thyroid hormone analog that binds to thyroid hormone receptors TRα1 and TRβ1 with high affinity, inducing α-myosin heavy chain mRNA expression. It is a valuable research tool for studying thyroid hormone signaling in cardiovascular research and metabolic studies, applicable in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1158-10-7
• MW: 510.06
• Purity: 99.35% (May vary between batches)
• Formula: C₁₅H₁₂I₂O₄
• SMILES: OC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
• Target: Thyroid hormone receptor(THR)
• Solubility: DMSO:140 mg/mL (274.48 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.92 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Ditpa cpd, C 082182, C082182, C-082182, 3,5Diiodothyropropionic acid, 3,5-Diiodothyropropionic acid, 3,5 Diiodothyropropionic acid, THR, Thyroid hormone receptor, Thyroid Hormone Receptor, Thyroid hormone receptor(THR), Thyroidhormonereceptor, Thyroidhormonereceptor(THR), TRα, TRβ

Compound Identifiers

PubChem CID

160565