3,5-Bis(4-nitrophenoxy)benzoic acid

SKU: orb1305851

Description

Compound W is a γ-secretase inhibitor that effectively reduces the production of Aβ42 and Nβ25 peptides. This small molecule is a valuable research tool for studying Alzheimer's disease pathology and Notch signaling in both cellular and biochemical assays.

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 173550-33-9
• MW: 396.31
• Purity: 99.71% (May vary between batches)
• Formula: C₁₉H₁₂N₂O₈
• SMILES: OC(=O)c1cc(Oc2ccc(cc2)[N+]([O-])=O)cc(Oc2ccc(cc2)[N+]([O-])=O)c1
• Target: Gamma-secretase
• Solubility: DMSO:50 mg/mL (126.16 mM);1.1eq. NaOH:< 19.81 mg/mL

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Compound W, 3,5 Bis(4 nitrophenoxy)benzoic acid, 3,5Bis(4nitrophenoxy)benzoic acid, 3,5-Bis(4-nitrophenoxy)benzoic acid, Aβ-like, Aβ42, Gamma secretase, Gammasecretase, hypothyroidism, notch-1, Inhibitor, inhibit, γ secretase, γ-secretase, peptide

Compound Identifiers

PubChem CID

16760376