3',4',7-Trihydroxyisoflavone

SKU: orb1684870

Description

3',4',7-Trihydroxyisoflavone is a soy-derived isoflavone that acts as an inhibitor of Cot (MAP3K8) and MKK4. It exhibits anticancer and antiangiogenic properties in vitro and has been shown in murine studies to enhance memory via cholinergic and BDNF pathways, as well as improve glucocorticoid-impaired skin barrier function relevant to atopic dermatitis research.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 485-63-2
• MW: 270.24
• Purity: 99.91% (May vary between batches)
• Formula: C₁₅H₁₀O₅
• SMILES: Oc1ccc2c(c1)occ(-c1ccc(O)c(O)c1)c2=O
• Target: JNK,MAPK,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.21 mM);DMSO:80 mg/mL (296.03 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MKK4, MAP3K8, 3',4',7-Trihydroxyisoflavone, 3',4',7Trihydroxyisoflavone, 3',4',7 Trihydroxyisoflavone

Compound Identifiers

PubChem CID

5284648