3,4,5-Tricaffeoylquinic acid

SKU: orb1684871

Description

This research compound, 3,4,5-Tricaffeoylquinic acid, suppresses TLR4 expression to inhibit Akt, ERK, and NF-κB pathway activation, thereby reducing TNF-α and LPS-induced inflammatory mediator production in keratinocytes. It is a useful tool for studying inflammatory skin disease mechanisms in both cellular and animal models.

Research Area

Cell Biology, Infectious Disease & Virology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 86632-03-3
• MW: 678.59
• Formula: C₃₄H₃₀O₁₅
• SMILES: OC(=O)[C@@]1(O)C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H](C1)OC(=O)\C=C\c1ccc(O)c(O)c1
• Target: TNF,HIV Protease,Akt,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

6440783