(32-Carbonyl)-RMC-5552

SKU: orb1690937

Description

(32-Carbonyl)-RMC-5552 is a potent dual mTORC1/2 inhibitor, strongly suppressing phosphorylation of p70S6K, 4E-BP1, and AKT (S473). This compound is a valuable chemical probe for studying mTOR signaling in cancer research and has demonstrated efficacy in preclinical in vivo tumor models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2382768-55-8
• MW: 1776.141
• Formula: C₉₃H₁₃₄N₁₀O₂₄
• SMILES: [H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)N2CCc3cc(Cn4nc(-c5ccc6oc(N)nc6c5)c5c(N)ncnc45)ccc3C2)[C@@H](C1)OC
• Target: Others,mTOR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162642651