3-Phenylpropyl isothiocyanate

SKU: orb1303285

Description

3-Phenylpropyl isothiocyanate is a potent chemopreventive agent that strongly inhibits NMBA-induced tumorigenesis. It is used in cancer chemoprevention research, with studies demonstrating its efficacy in both in vitro assays and in vivo animal models of esophageal carcinogenesis.

Key Properties

• CAS Number: 2627-27-2
• MW: 177.27
• Purity: 99.82% (May vary between batches)
• Formula: C₁₀H₁₁NS
• SMILES: C(CCN=C=S)C1=CC=CC=C1
• Target: Others
• Solubility: DMSO:50 mg/mL (282.06 mM)

Bioactivity

• In Vivo:
  3-Phenylpropyl isothiocyanate (5, 1, or 0.2 μmol; gavage; A/J mice; daily for 4 consecutive days prior to administration of 10 μmol of NNK by i.p. injection) effectively inhibits NNK-induced lung tumors. In vivo, 3-Phenylpropyl isothiocyanate decreases lung tumor formation induced by benzo[a]pyrene and NNK .
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

chemopreventive, 3 Phenylpropyl isothiocyanate, 3Phenylpropyl isothiocyanate, 3-Phenylpropyl isothiocyanate, lung, inhibit, Inhibitor, tumorigenesis

Compound Identifiers

PubChem CID

75815