3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine

SKU: orb1907868

Description

This is a protected 2'-deoxyadenosine derivative, featuring a tert-butyldimethylsilyl (TBDMS) group at the 3'-O position and a dimethoxytrityl (DMT) group at the 5'-O position, while the amino and 3'-OH groups remain available for further reaction. It serves as a key synthetic intermediate in oligonucleotide chemistry, specifically for solid-phase synthesis of DNA and antisense oligonucleotides for in vitro and in vivo research applications.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 89947-86-4
• MW: 667.87
• Formula: C₃₇H₄₅N₅O₅Si
• SMILES: C(OC[C@@H]1[C@@H](O[Si](C(C)(C)C)(C)C)C[C@@H](O1)N2C=3C(N=C2)=C(N)N=CN3)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
• Target: Nucleoside Antimetabolite/Analog,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11093601