3-O-Methylgalangin

SKU: orb1301565

Description

3-O-Methylgalangin

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 6665-74-3
• MW: 284.26
• Purity: 98.24%
• Formula: C₁₆H₁₂O₅
• SMILES: COc1c(oc2cc(O)cc(O)c2c1=O)-c1ccccc1
• Target: Antibacterial
• Solubility: DMSO:25 mg/mL (87.95 mM);10% DMSO+90% Corn Oil:1 mg/mL (3.52 mM)

Bioactivity

• In Vitro:
  GALANGIN-3-METHYLETHER markedly reduce the viability of Leishmania amastigotes.
• Cell Research:
  L. amazonensis amastigotes were maintained and cultured axenically.Washed parasites were resuspended in RPMI-1640 medium supplemented with 4% fetal calf serum, pH 5.0, and incubated at 33 C for 18 h with crude extracts (1 mg/mL) or isolated compounds(GALANGIN-3-METHYLETHER) (0.014, 0.084, 0.5, and 1.0 mg/mL) dissolved in dimethyl sulfoxide (DMSO)/RPMI-1640 (1:99) the amastigote viability was assessed colorimetrically b the reduction of a tetrazolium salt (MTT) as. Absorbances were expressed as percentages relative to untreated controls. Amphotericin B (0.02 mg/mL) was used a the positive control and DMSO/RPMI-1640 (1:99) as negative control the bioassays were carried out in triplicate.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, 3-Methylgalangin, 3OMethylgalangin, 3-O-Methylgalangin, 3 O Methylgalangin, Inhibitor, inhibit, Galangin 3-methyl ether, GALANGIN-3-METHYLETHER

Compound Identifiers

PubChem CID

5281946