3-Deoxyaconitine

SKU: orb1302299

Description

3-Deoxyaconitine, a derivative of Aconitine, acts as a tetrodotoxin-sensitive sodium channel activator. This induces presynaptic depolarization to block nerve action potentials and inhibit neurotransmitter release, thereby reducing end plate potentials at neuromuscular junctions. It is a research tool for studying ion channel function and synaptic transmission in neuropharmacology.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3175-95-9
• MW: 629.74
• Purity: 99.76%
• Formula: C₃₄H₄₇NO₁₀
• SMILES: [H][C@@]12C[C@@]3(O)[C@H](OC(=O)c4ccccc4)[C@]1([H])[C@@](OC(C)=O)(C1[C@H](OC)[C@@]4([H])C22C1N(CC)C[C@]4(COC)CC[C@@H]2OC)[C@@H](O)[C@@H]3OC
• Target: Sodium Channel
• Solubility: DMSO:50 mg/mL (79.4 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.18 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SodiumChannel, Sodium Channel, inhibit, Na channels, Na+ channels, Inhibitor, 3 Deoxyaconitine, 3Deoxyaconitine, 3-Deoxyaconitine

Compound Identifiers

PubChem CID

78358503