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(2R,3S)-PD-1/PD-L1-IN-38

SKU: orb3141563

Description

(2R,3S)-PD-1/PD-L1-IN-38 (Compound (±)-13e) is an orally active Ah receptor (AhR) antagonist with both in vivo and in vitro anticancer properties. This compound enhances the secretion of INF-γ by CD8+ T cells and inhibits PD-1/PD-L1 signaling.

Research Area

Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation

Images & Validation

Key Properties

FormulaC29H28O4
TargetAryl Hydrocarbon Receptor,PD-1/PD-L1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information