(2R,3S)-Emricasan

SKU: orb2663689

Description

(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan. This compound acts as an orally effective irreversible pan-caspase inhibitor. (2R,3S)-Emricasan inhibits the increase in caspase-3 activity induced by Zika virus (ZIKV) and protects human cortical neural progenitor cells.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 409369-54-6
• MW: 569.5
• Formula: C₂₆H₂₇F₄N₃O₇
• SMILES: N(C(C(N[C@@H](C(N[C@H](C(COC1=C(F)C(F)=CC(F)=C1F)=O)CC(O)=O)=O)C)=O)=O)C2=C(C(C)(C)C)C=CC=C2
• Target: Caspase

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase