2DII

SKU: orb2945110

Description

2DII is a potent and selective mTORC2 inhibitor that functions by binding to the mSin1 PH domain, thereby reducing AKT1 phosphorylation. It is a valuable research tool for studying mTORC2 signaling in cancer metabolism and cellular growth, applicable in both in vitro and in vivo experimental models.

Research Area

Signal Transduction

Key Properties

• MW: 1066.74
• Formula: C₅₄H₇₆ClN₇O₁₁S
• SMILES: CCCCCC/C=C\CCCCCCCC(=O)NC[C@@H](C(=O)N)NC(=O)COCCOCCNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H]2CCCN2C(=O)C3=CC(=C(C=C3)OC)S(=O)(=O)NCC4=CC=C(C=C4)Cl
• Target: mTOR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676929