2,5-Dihydroxybenzaldehyde

SKU: orb1297140

Description

This small molecule, 2,5-Dihydroxybenzaldehyde (Gentisaldehyde), exhibits antioxidant properties and demonstrates antimicrobial activity. It is reported to be active against Mycobacterium avium subsp. paratuberculosis and inhibits Staphylococcus aureus strains with an MIC50 of 500 mg/L, making it a compound of interest for infectious disease research.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 1194-98-5
• MW: 138.12
• Purity: 99.55% (May vary between batches)
• Formula: C₇H₆O₃
• SMILES: OC1=CC(C=O)=C(O)C=C1
• Target: Anti-infection|||Antibacterial
• Solubility: DMSO:30 mg/mL (217.2 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (14.48 mM)

Bioactivity

• Target IC50:
  S. aureus:500 mg/L(MIC50)
• In Vitro:
  2,5-Dihydroxybenzaldehyde modified the three lipid monolayer structures by integrating into the monolayer, forming aggregates of antimicrobial -lipid complexes, reducing the packing effectiveness of the lipids, increasing the membrane fluidity, and altering the total dipole moment in the monolayer membrane model. The interactions of 2,5-Dihydroxybenzaldehyde with bacterial phospholipids depended on both the structure of the antimicrobials and the composition of the monolayers.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bovine, Antimicrobial, antiseptic, Antifection, Anti-infection, Antiinfection, Bacterial, 2,5Dihydroxybenzaldehyde, 2,5-Dihydroxybenzaldehyde, 2,5 Dihydroxybenzaldehyde, inhibit, ions, mastitis, Inhibitor, Gentisaldehyde, S. aureus, phosphate

Compound Identifiers

PubChem CID

70949