244cis

SKU: orb2283561

Description

244cis, an ionizable cationic lipid incorporating a piperazine structure, facilitates the creation of lipid nanoparticles (LNPs). These LNPs, when formulated with 244cis and coated with an mRNA reporter gene, exhibit preferential accumulation in the lungs of mice, in contrast to those formulated with SM-102. Additionally, it leads to a reduction in the levels of serum chemokine (C-C motif) ligand 2 (CCL2).

Key Properties

• CAS Number: 2956402-64-3
• MW: 970.54
• Formula: C₆₀H₁₁₁N₃O₆
• SMILES: C(CN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CCCCCCCCC(OC/C=C\CCCCCC)=O)N1CCN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CC1
• Target: Others,Liposome

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others,Liposome