2,2,5,7,8-Pentamethyl-6-Chromanol

SKU: orb1308730

Description

2,2,5,7,8-Pentamethyl-6-chromanol (PMC) is the antioxidant structural core of α-tocopherol (vitamin E). It functions as a potent modulator of androgen receptor (AR) signaling and exhibits anti-cancer activity in prostate cancer cell lines in vitro. This small molecule is a valuable research tool for studying AR pathways and oxidative stress in oncology.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 950-99-2
• MW: 220.31
• Purity: 99.30% (May vary between batches)
• Formula: C₁₄H₂₀O₂
• SMILES: Cc1c(C)c2OC(C)(C)CCc2c(C)c1O
• Target: NF-κB,Androgen Receptor
• Solubility: DMSO:250 mg/mL (1134.76 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (22.7 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2,2,5,7,8 Pentamethyl 6 Chromanol, 2,2,5,7,8Pentamethyl6Chromanol, 2,2,5,7,8-Pentamethyl-6-Chromanol, Androgen Receptor, AndrogenReceptor, Inhibitor, PMC, inhibit

Compound Identifiers

PubChem CID

99479