20(R)-Propanaxadiol

SKU: orb1222304

Description

R-Ginsenodie Rg3 γ2 GABA-A receptor agonist, 7.1 K+ channel activator, α10 nAChR antagonist found in Panax. It exhibits a wide variety of biological activities, including decreasing expression of pro-inflammatory cytokines, reducing oxidative stress, and inhibiting tubular formation and migration of endothelial progenitor cells.

Key Properties

• CAS Number: 38243-03-7
• MW: 785.02
• Purity: >98% (HPLC)
• Formula: C₄₂H₇₂O₁₃
• SMILES: C1[C@@H](C([C@H]2[C@](C1)([C@@H]1[C@@](CC2)([C@]2([C@H]([C@@H](C1)O)[C@H](CC2)[C@@](C)(CCC=C(C)C)O)C)C)C)(C)C)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)O)O)CO
• Target: DNA/RNA Synthesis
• Solubility: In Vitro: DMSO : 41.67 mg/mL (53.08 mM)

Bioactivity

• In Vivo:
  Animal model: Male Kunming mice weighing 18-22 g. Dosage: 0.05 mg/kg, 0.1 mg/kg, 0.5 mg/kg (5 μL each nostril). Administration: Intranasal administration; for 2 weeks. Result: Significantly prolonged the weight-loaded swimming time, and also increased the hepatic glycogen levels.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

DNA/RNA Synthesis