2-tert-Butyl-1,4-benzoquinone

SKU: orb1296998

Description

2-tert-Butyl-1,4-benzoquinone (TBQ) is an electrophilic metabolite of BHA known to activate the Nrf2 pathway via S-arylation of Keap1 in RAW264.7 cells. This mechanism makes it a valuable tool for studying oxidative stress response, Nrf2 signaling, and cytoprotective gene regulation in both cellular and biochemical research models.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 3602-55-9
• MW: 164.2
• Purity: 99.29%
• Formula: C₁₀H₁₂O₂
• SMILES: CC(C)(C)C1=CC(=O)C=CC1=O
• Target: Apoptosis,Nrf2
• Solubility: DMSO:60 mg/mL (365.41 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2tertButyl1,4benzoquinone, 2-tert-Butyl-1,4-benzoquinone, 2 tert Butyl 1,4 benzoquinone, Nrf2

Compound Identifiers

PubChem CID

19211