2′-O-Methylcytidine

SKU: orb1303700

Description

This compound acts as a competitive inhibitor of the HCV NS5B RNA-dependent RNA polymerase, effectively blocking RNA synthesis in biochemical assays. It demonstrates antiviral activity by inhibiting hepatitis C virus RNA replication in cellular models, making it a useful tool for virology and antiviral drug discovery research.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry

Key Properties

• CAS Number: 2140-72-9
• MW: 257.24
• Purity: 99.81% (May vary between batches)
• Formula: C₁₀H₁₅N₃O₅
• SMILES: CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(N)nc1=O
• Target: HCV Protease|||Nucleoside Antimetabolite/Analog
• Solubility: H2O:62.5 mg/mL (242.96 mM);PBS (pH 7.2):10 mg/mL (38.87 mM);DMSO:0.2 mg/mL (0.78 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RNA synthesis, Inhibitor, Hepatitis C virus, HCV, HCV replication, HCVProtease, HCV Protease, inhibit, NucleosideAntimetabolite, Nucleoside Antimetabolite/Analog, Nucleoside Antimetabolite, nucleoside, 2′ O Methylcytidine, 2′OMethylcytidine, 2′-O-Methylcytidine, Analog

Compound Identifiers

PubChem CID

150971