2-Methoxyestrone

SKU: orb1308893

Description

2-Methoxyestrone is a methoxylated catechol estrogen primarily formed from 2-hydroxyestrone. As a key metabolite of estradiol, it is studied in endocrinology and oncology research for its potential roles in cell proliferation and receptor interactions, both in vitro and in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 362-08-3
• MW: 300.39
• Purity: 99.51% (May vary between batches)
• Formula: C₁₉H₂₄O₃
• SMILES: [H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3cc(OC)c(O)cc3CC[C@@]21[H]
• Target: Endogenous Metabolite
• Solubility: DMSO:44 mg/mL (146.48 mM)

Bioactivity

• In Vivo:
  2-Methoxyestrone, given at noon of proestrus, significantly augments the magnitude of the preovulatory prolactin rise possibly by inhibiting the formation of endogenous 2-hydroxyestrogens in the brain.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2Methoxyestrone, 2-Methoxyestrone, 2 Methoxyestrone, inhibit, Human Endogenous Metabolite, EndogenousMetabolite, Endogenous Metabolite, Inhibitor

Compound Identifiers

PubChem CID

440624