2-Hydroxybutyric acid

SKU: orb1945026

Description

2-Hydroxybutyric acid (α-Hydroxybutyric acid) is an organic acid metabolite involved in protein catabolism. It serves as a significant biomarker in metabolic research, particularly for studies on type 2 diabetes and pre-eclampsia, and is utilized in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 600-15-7
• MW: 104.105
• Purity: 98.00% (May vary between batches)
• Formula: C₄H₈O₃
• SMILES: CCC(O)C(O)=O
• Target: Endogenous Metabolite
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (19.21 mM);DMSO:50 mg/mL (480.31 mM)

Bioactivity

• In Vivo:
  2-Hydroxybutyric acid（250 mg/kg；i.p. for 3 days）Prevented AP-induced liver injury in C57 mice.
• In Vitro:
  2-Hydroxybutyric acid (0-40 mM; 24-48 hours) can decrease AP-induced toxicity in AML12, BRL3A, and primary hepatocytes from mice.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EndogenousMetabolite, Endogenous Metabolite, Compound T4322, Compound T-4322, Compound T 4322, α-Hydroxybutyric acid

Compound Identifiers

PubChem CID

11266