2'-Fluorothymidine

SKU: orb1706314

Description

2'-Fluorothymidine is a selective substrate for thymidine kinase 2 (TK2), structurally related to thymidine and methyluridine. It is used in vitro and in vivo to study nucleoside metabolism, TK2 activity, and cellular proliferation, particularly in mitochondrial DNA depletion syndromes and oncology research.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 122799-38-6
• MW: 260.22
• Purity: 99.67% (May vary between batches)
• Formula: C₁₀H₁₃FN₂O₅
• SMILES: Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2F)c(=O)[nH]c1=O
• Target: Others
• Solubility: DMSO:55 mg/mL (211.36 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

2'-Deoxy-2'-fluoro-5-Methyluridine, 2'-​Deoxy-​2'-​fluoro-​5-​Methyluridine, 2'-Fluorothymidine

Compound Identifiers

PubChem CID

159498