2-Di-1-ASP

SKU: orb1219592

Description

2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G4 structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-myc, c-kit87up).

Key Properties

• CAS Number: 2156-29-8
• MW: 366.24
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₉IN₂
• SMILES: [I-].CN(C)c1ccc(\C=C\c2cccc[n+]2C)cc1
• Target: Others
• Solubility: DMSO:24 mg/mL (65.53 mM; Need ultrasonic)

Bioactivity

• In Vitro:
  2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G-quadruplex (G4) structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-kit87up, c-myc).
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Others