2′-Deoxy-GDP trisodium

SKU: orb3180965

Description

2′-Deoxy-GDP trisodium is a guanosine monophosphate (GMP) analog that acts as an inhibitor of hypoxanthine phosphoribosyltransferase (HGPRT), with an IC50 of 12.5 μM. HGPRT is a key enzyme in the purine metabolic pathway of all protozoan parasites.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 102783-74-4
• MW: 493.15
• Purity: 99.91% (May vary between batches)
• Formula: C₁₀H₁₂N₅Na₃O₁₀P₂
• SMILES: O=C1C2=C(NC(N)=N1)N([C@@H]3O[C@@H]([C@H](C3)O)COP(OP([O-])([O-])=O)([O-])=O)C=N2.[Na+].[Na+].[Na+]
• Target: Nucleoside Antimetabolite/Analog,Parasite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Nucleoside Antimetabolite/Analog,Parasite