2-Cyanopyrimidine

SKU: orb1299809

Description

This small molecule is a potent and selective inhibitor of cathepsin K, demonstrating an IC50 of 170 nM. It is a valuable chemical tool for investigating osteoclast function in bone resorption research, applicable in both in vitro enzymatic assays and cellular studies.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 14080-23-0
• MW: 105.1
• Purity: 99.27% (May vary between batches)
• Formula: C₅H₃N₃
• SMILES: N#CC1=NC=CC=N1
• Target: Cysteine Protease
• Solubility: DMSO:11 mg/mL (104.66 mM)

Bioactivity

• Target IC50:
  Cathepsin:170 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cysteine Protease, cysteine, CysteineProtease, Cathepsin K, Cathepsin, 2 Cyanopyrimidine, 2-Cyanopyrimidine, 2-cyano-Pyrimidine, 2Cyanopyrimidine, inhibit, Inhibitor, protease, osteoporos

Compound Identifiers

PubChem CID

2757979