2-Bromo-LSD D-Tartrate

SKU: orb3211447

Description

2-Bromo-LSD D-Tartrate is a compound that penetrates the blood-brain barrier and acts as a partial agonist and competitive partial antagonist of 5-HT2A receptors. It exhibits strong partial agonist activity at 5-HT2A receptors (EC50 for Gq dissociation = 0.81 nM) and potent partial antagonist activity (KB for Gq dissociation = 0.18 nM). The compound demonstrates partial agonist effects on various aminergic GPCRs, including 5-HT2A, but lacks 5-HT2B agonism. Additionally, 2-Bromo-LSD D-Tartrate induces dendritogenesis and spinogenesis and reverses behavioral effects of chronic stress, enhancing active coping behaviors in mice.

Key Properties

• CAS Number: 2855123-30-5
• MW: 954.74
• Formula: C₄₄H₅₄Br₂N₆O₈
• SMILES: OC([C@@H](O)[C@H](O)C(O)=O)=O.BrC1=C2C3=C(N1)C=CC=C3C4=C[C@@H](C(N(CC)CC)=O)CN(C)[C@]4([H])C2.BrC5=C6C7=C(N5)C=CC=C7C8=C[C@@H](C(N(CC)CC)=O)CN(C)[C@]8([H])C6
• Target: GPCR19,5-HT Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GPCR19,5-HT Receptor