2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC

SKU: orb1298534

Description

This small molecule is a potent and selective inhibitor of IKKβ, a key kinase in the NF-κB signaling pathway. It is a valuable research tool for studying inflammatory responses, immune regulation, and related diseases in both cellular and biochemical assays.

Research Area

Signal Transduction

Key Properties

• CAS Number: 4815-35-4
• MW: 218.275
• Purity: 99.48% (May vary between batches)
• Formula: C₁₁H₁₀N₂OS
• SMILES: NC(=O)C1=C(N)SC(=C1)C1=CC=CC=C1
• Target: IκB/IKK
• Solubility: DMSO:22.5 mg/mL (103.08 mM)

Bioactivity

• Target IC50:
  IKKβ:1.9 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IκB, IKK, IkB, IkB/IKK, IKKβ, 2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC, 2AMINO5PHENYLTHIOPHENE3CARBOXYLIC, 2 AMINO 5 PHENYL THIOPHENE 3 CARBOXYLIC

Compound Identifiers

PubChem CID

703965