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2-5A

SKU: orb3135596

Description

2-5A is a 5'-triphosphorylated (2',5') oligoadenylate. It acts as an immune messenger capable of enhancing RNase L immunity. By binding to RNase L and activating its endoribonuclease activity, 2-5A degrades viral mRNA and inhibits protein synthesis. This compound is useful in research on respiratory syncytial virus (RSV) and cancer.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Images & Validation

Key Properties

CAS Number65954-93-0
MW1165.59
FormulaC30H40N15O25P5
SMILESO(P(OC[C@H]1O[C@H]([C@H](OP(OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=4C(N=C3)=C(N)N=CN4)(=O)O)[C@@H]1O)N5C=6C(N=C5)=C(N)N=CN6)(=O)O)[C@H]7[C@@H](O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]7O)N8C=9C(N=C8)=C(N)N=CN9
TargetRSV,DNA/RNA Synthesis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information