(1S,2S)-ML-SI3

SKU: orb2567310

Description

(1S,2S)-ML-SI3 is the (-)-trans-isomer and a potent TRPML1/2 inhibitor, with weaker activity against TRPML3. Its (+)-enantiomer conversely inhibits TRPML1 but activates TRPML2/3. This stereospecific modulation makes it a valuable chemical tool for studying lysosomal ion channel function in cellular and biochemical assays.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2563870-87-9
• MW: 429.58
• Formula: C₂₃H₃₁N₃O₃S
• SMILES: N(S(=O)(=O)C1=CC=CC=C1)[C@@H]2[C@H](CCCC2)N3CCN(CC3)C4=C(OC)C=CC=C4
• Target: TRP/TRPV Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

94784693