(1S,2S)-Bortezomib

SKU: orb1940843

Description

(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the proteasome with a Ki of 0.6 nM for 20S proteasome.(In Vitro):Bortezomib disrupts the cell cycle, induces apoptosis, inhibits NF-κB, and possesses anti-cancer capacity.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1132709-14-8
• MW: 384.24
• Purity: >98% (HPLC)
• Formula: C₁₉H₂₅BN₄O₄
• SMILES: [C@H](CC1=CC=CC=C1)(C(N[C@H](CC(C)C)B(O)O)=O)NC(=O)C=2C=NC=CN2
• Target: Proteasome
• Solubility: In Vitro: DMSO : 50 mg/mL (130.13 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bortezomib

Quick Database Links

Gene Symbol

Proteasome