(1S)-CCR2 antagonist 1

SKU: orb2283509

Description

(1S)-CCR2 antagonist 1 is the levorotatory enantiomer of a potent CCR2 antagonist, demonstrating high binding affinity (Ki = 2.4 nM) and an extended receptor residence time. This compound is a valuable research tool for investigating CCR2-mediated pathways in inflammatory and autoimmune diseases, applicable in both in vitro binding assays and in vivo model studies.

Research Area

Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1683534-97-5
• MW: 549.47
• Formula: C₂₈H₃₂BrF₃N₂O
• SMILES: C(=O)([C@]1([C@@H](C)C)C[C@H](N[C@@H]2C=3C(CC2)=CC(Br)=CC3)CC1)N4CC=5C(CC4)=CC=C(C(F)(F)F)C5
• Target: CCR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

118734690