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σ1R/H3R ligand-1

SKU: orb3211271

Description

The compound σ1R/H3R ligand-1 is a dual σ1R/H3R antagonist with a σ1RKi of 8.8 nM and an H3RKi of 31.2 nM. It demonstrates potent, dose-dependent analgesic activity in mouse models of visceral and neuropathic pain through its simultaneous antagonistic effect on σ1R and H3R. σ1R/H3R ligand-1 is useful for research on visceral and neuropathic pain.

Images & Validation

Key Properties

TargetHistamine Receptor,Sigma receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information