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(1R,2S,7R)-Sitafloxacin

SKU: orb3028862

Description

(R)-Sitafloxacin (DU-6857) is an enantiomer of Sitafloxacin (DU-6859a) and functions as a topoisomerase inhibitor, demonstrating an IC50 of 0.18 μg/mL against DNA gyrase.

Research Area

Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number127254-10-8
MW409.814
FormulaC19H18ClF2N3O3
SMILESN[C@@H]1C2(CN(C1)C=3C(Cl)=C4N(C=C(C(O)=O)C(=O)C4=CC3F)[C@H]5[C@@H](F)C5)CC2
TargetAntibacterial,Topoisomerase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information