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19-Nor-22-oxa-1a,25(OH)2-VD3

SKU: orb3174485

Description

19-Nor-22-oxa-1a,25(OH)2-VD3 is a vitamin D₃ analog characterized by its extremely low affinity for the vitamin D receptor (VDR) and minimal binding to the vitamin D binding protein (DBP). It is effective in inducing differentiation in HL-60 cells and causes cell cycle arrest at the G₀-G₁ phase. This compound can be utilized in research pertaining to diseases such as hyperparathyroidism.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number284041-36-7
MW406.61
FormulaC25H42O4
SMILESC[C@@]12[C@](\C(=C\C=C3C[C@@H](O)C[C@H](O)C3)\CCC1)(CC[C@@]2([C@@H](OCCC(C)(C)O)C)[H])[H]
TargetVitamin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information