18α-Glycyrrhetinic acid

SKU: orb1305082

Description

Enoxolone (18α-Glycyrrhetinic acid) is a multifunctional small molecule that inhibits NF-κB and activates the proteasome. It has been studied in vitro and in vivo for its roles in promoting longevity, reducing protein aggregation, and inducing apoptosis in various research models.

Research Area

Cell Biology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 1449-05-4
• MW: 470.68
• Purity: 99.83%
• Formula: C₃₀H₄₆O₄
• SMILES: [H][C@]12C[C@](C)(CC[C@]1(C)CC[C@]1(C)C2=CC(=O)[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)C3CC[C@@]12C)C(O)=O
• Target: Apoptosis,Proteasome,NF-κB
• Solubility: DMSO:10.64 mg/mL (22.61 mM)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Proteasome, Nuclear factor-κB, Nuclear factor-kappaB, NF-κB, NF-kB, NFκB, NFkB, inhibit, Glycyrrhetinic acid, Enoxolone, Inhibitor, 18a-Glycyrrhetinic acid, 18alpha-Glycyrrhetinic acid, 18α Glycyrrhetinic acid, 18αGlycyrrhetinic acid, 18α-Glycyrrhetinic acid, Apoptosis

Compound Identifiers

PubChem CID

12193680