17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid

SKU: orb1984945

Description

This specialized metabolite of DHA is generated via aspirin-triggered COX-2 and lipoxygenase pathways. It functions as a PPARγ agonist (EC50 ~200 nM) and activates Nrf2, promoting antioxidant responses while suppressing pro-inflammatory mediators like cytokines and nitric oxide in the 5-25 µM range, making it relevant for inflammation and oxidative stress research.

Research Area

Immunology & Inflammation, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 1233715-28-0
• MW: 342.479
• Formula: C₂₂H₃₀O₃
• SMILES: CC\C=C/CC(=O)\C=C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O
• Target: Nrf2,Others,PPAR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

45105201