17β-Hydroxywortmannin

SKU: orb2283720

Description

17β-Hydroxywortmannin is a potent, orally bioavailable inhibitor of PI-3-kinase with an IC50 of 0.5 nM. It inhibits osteoclast-mediated bone resorption (IC50=10 nM) and exhibits antitumor activity, making it a valuable tool for researching cancer, bone metabolism, and PI3K signaling pathways in both cellular and animal models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 58053-83-1
• MW: 430.45
• Formula: C₂₃H₂₆O₈
• SMILES: C[C@@]12C3=C([C@]4([C@](C)(C[C@H]3OC(C)=O)[C@@H](O)CC4)[H])C(=O)C5=C1C(C(=O)O[C@@H]2COC)=CO5
• Target: PI3K,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9867340