17-Demethoxy-reblastatin

SKU: orb2665463

Description

17-Demethoxy-reblastatin (17-DR) is an Hsp90 inhibitor that demonstrates anti-cancer activity in vitro by inhibiting proliferation and colony formation in HepG2 and SMMC7721 cells. It induces apoptosis through a mitochondrial and caspase-dependent pathway, making it a useful tool for oncology and molecular chaperone research.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 299173-64-1
• MW: 518.64
• Formula: C₂₈H₄₂N₂O₇
• SMILES: CO[C@H]1CC\C=C(C)/C(=O)NC2=CC(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)\C=C(C)\[C@H]1OC(N)=O)=CC(O)=C2
• Target: Apoptosis,HSP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176419166