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15(S)-HEPE

SKU: orb1693032

Description

15(S)-HEPE is a 15-lipoxygenase-derived metabolite of eicosapentaenoic acid (EPA). This oxylipin acts as a 5-lipoxygenase inhibitor in vitro, as demonstrated in RBL-1 cells (IC50 ~28 µM), and serves as a key intermediate in the biosynthesis of specialized pro-resolving mediators, making it relevant for inflammation and resolution research.

Images & Validation

Key Properties

CAS Number86282-92-0
MW318.45
FormulaC20H30O3
SMILESC(=C/C=C\C/C=C\C/C=C\CCCC(O)=O)\[C@H](C/C=C\CC)O
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • (±)15-HEPE [orb1985137]

    88852-33-9

    318.45

    C20H30O3

    25 μg (314.0 μM x 250 μl in ethanol), 100 μg (314.0 μM x 1000 μl in ethanol), 50 μg (314.0 μM x 500 μl in ethanol), 250 μg (314.0 μM x 2.5 ml in ethanol)
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Key Properties

No computed properties available.

Protocol Information