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15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester

SKU: orb3135956

Description

15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivative of 15-Deoxy-Δ-12,14-prostaglandin J2. The 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. This compound acts as a selective PPARγ (with an EC50 of 2 µM) and covalent PPARδ agonist. Additionally, 15-Deoxy-Δ-12,14-prostaglandin J2 effectively promotes the differentiation of C3H10T1/2 fibroblasts into adipocytes, with an EC50 of 7 μM.

Research Area

Metabolism Research, Molecular Biology

Images & Validation

Key Properties

CAS Number1947405-90-4
MW390.51
FormulaC23H34O5
SMILESC(\C=C\CCCCC)=C/1\[C@@H](C/C=C\CCCC(OC(CO)CO)=O)C=CC1=O
TargetPPAR,Others,Endogenous Metabolite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information