1,3,5,8-Tetrahydroxyxanthone

SKU: orb1297564

Description

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin), a natural xanthone from Gentianella acuta, exhibits antispasmodic and anti-inflammatory properties. Research applications include in vitro studies demonstrating antibacterial activity against Staphylococcus aureus and mutagenicity assessments in Salmonella typhimurium strains.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 2980-32-7
• MW: 260.2
• Purity: 98.10% (May vary between batches)
• Formula: C₁₃H₈O₆
• SMILES: Oc1cc(O)c2c(c1)oc1c(O)ccc(O)c1c2=O
• Target: Anti-infection
• Solubility: DMSO:10 mg/mL (38.43 mM)

Bioactivity

• In Vitro:
  The mutagenicities of naturally occurring xanthones were tested in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method. Xanthydrol, gentisein, gentisin, isogentisin, 1-hydroxy-3,7-dimethoxyxanthone, 1,3,7-trimethoxyxanthone, Desmethylbellidifolin, bellidifolin and dimethylbellidifolin were mutagenic, but unsubstituted xanthone was not mutagenic to TA100, TA98, TA97 and TA2637 with or without a metabolic activation system

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

muscle, inhibit, Inhibitor, colitis, colon, Desmethylbellidifolin, 1,3,5,8 Tetrahydroxyxanthone, 1,3,5,8Tetrahydroxyxanthone, 1,3,5,8-Tetrahydroxyxanthone, Antiinfection, Anti-infection, anti-inflammatory, Antifection, antispasmodic, spasm, Xanthone, ulcerative

Compound Identifiers

PubChem CID

5281626