12R-LOX-IN-2

SKU: orb1944745

Description

12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein level of Ki67 and the mRNA expression of IL-17A in IMQ-induced cells. 12R-LOX-IN-2 may be useful in the study of psoriasis and other skin-associated inflammatory diseases.

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 3026677-37-9
• MW: 271.31
• Purity: 99.92%
• Formula: C₁₉H₁₃NO
• SMILES: OC=1C=CC(C2=NC=3C=CC=CC3C=C2)=C4C=CC=CC14
• Target: DNA/RNA Synthesis,Lipoxygenase
• Solubility: DMSO:50 mg/mL (184.29 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

12RLOXIN2, LOX

Compound Identifiers

PubChem CID

168679704