12R-LOX-IN-1

SKU: orb1941314

Description

12R-LOX-IN-1 (Compound 4a), with an IC50 of 28.25 µM, is an inhibitor of 12R-LOX. It suppresses hyperproliferation and colony formation in Imiquimod-induced psoriatic keratinocytes, and reduces levels of reactive oxygen species, Ki67, IL-17A, TNF-α, and IL-6. This compound has utility in antipsoriatic research.

Key Properties

• CAS Number: 857758-13-5
• MW: 237.25
• Formula: C₁₅H₁₁NO₂
• SMILES: OC=1C=CC=2N=C(C=CC2C1)C=3C=CC=CC3O
• Target: Others

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

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