123C4

SKU: orb1296577

Description

123C4 is a potent and selective small molecule agonist targeting the EPHA4 receptor tyrosine kinase, with a competitive binding affinity (Ki=0.65 µM). It is a valuable research tool for studying EPHA4 signaling in neurological disorders and cancer, applicable in both cellular and biochemical assays.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2034159-30-1
• MW: 807.34
• Purity: 98.94% (May vary between batches)
• Formula: C₄₃H₄₇ClN₈O₆
• SMILES: COc1ccc2[nH]cc(CCNC(=O)[C@H](Cc3ccncc3)NC(=O)[C@H](Cc3ccc(Cl)cc3)NC(=O)[C@H](Cc3c[nH]c4ccc(O)cc34)NC(=O)CCCN)c2c1
• Target: Ephrin Receptor
• Solubility: DMSO:252.5 mg/mL (312.76 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (6.19 mM)

Bioactivity

• Target IC50:
  EphA4:0.65 μM (Ki)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, EphrinReceptor, Ephrin Receptor, 123C4, 123C-4

Compound Identifiers

PubChem CID

122661600