1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin

• Catalog Number: orb2276877
• Category: Small Molecules
• Description: 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, a polychlorinated dibenzodioxin (PCDD), acts as an agonist for the aryl hydrocarbon receptor (AhR; EC50s = 5.4 and 9.3 nM at 4 and 8 h, respectively, in a reporter assay). It has been observed to reduce antibody production against sheep red blood cells in mice at doses of 0.5 and 2 µg/kg. This compound has been detected in animal feed and in the vicinity of municipal waste incinerators.
• Purity: 98.00%
• MW: 390.86
• Biological Activity: 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, a polychlorinated dibenzodioxin (PCDD), acts as an agonist for the aryl hydrocarbon receptor (AhR; EC50s = 5.4 and 9.3 nM at 4 and 8 h, respectively, in a reporter assay). It has been observed to reduce antibody production against sheep red blood cells in mice at doses of 0.5 and 2 µg/kg. This compound has been detected in animal feed and in the vicinity of municipal waste incinerators.
• CAS Number: 57653-85-7
• Formula: C₁₂H₂Cl₆O₂
• SMILES: ClC1=C(Cl)C=C2OC3=C(C=C(C(Cl)=C3Cl)Cl)OC2=C1Cl
• Storage: -20°C
• Note: For research use only