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12-Hydroxynevirapine

SKU: orb1982688

Description

12-Hydroxynevirapine is a key oxidative metabolite of the antiviral drug Nevirapine. It is bioactivated by sulphotransferases (SULTs) to form the reactive 12-sulphoxy-nevirapine, a process studied to understand Nevirapine's idiosyncratic hepatotoxicity and skin rash adverse effects in both in vitro and in vivo research models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number133627-24-4
MW282.3
FormulaC15H14N4O2
SMILESOCc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Nevirapine [orb1226598]

    >98% (HPLC)

    129618-40-2

    266.2979

    C15H14N4O

    5 mg, 10 mg, 50 mg, 200 mg, 100 mg, 500 mg, 1 g
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Key Properties

No computed properties available.

Protocol Information